(a) A small introduction: Some members of the heat resistant
genus Camplyobacter are food-borne pathogens. They have been isolated
with increased frequencies from food and also from fecal samples collected
from patients suffering from acute diarrheal diseases. Their epidemiology,
natural habitats and the mechanism of infection is unclear and stems from
the problem that they are fastidious and their culture has been time consuming
and complex. The identification and differentiation of different pathogenic
species is also difficult (approximately 90%).
(b) Suggested information for inclusion: The intention of the
topic is to summarise the knowledge currently available for pathogenic
Campylobacter species. I have included below some suggestions
that may assist you in writing this summary. You may also come across other
interesting facts during the course of your reading that you may wish to
add to your summary.
(c) Suggested reading list to get you started:
Campylobacter systematics and classification; name the pathogenic
Habitats and growth in nature
Suggested evolution and phylogeny
Method of cultivation
Mechanism of heat resistance
Mechanism of pathogenicity (include cell or animal models if known)
Techniques for detection and identification. Discuss advantages and disadvantages
of serological and molecular techniques in your write up. Also write on
some promising developments in rapid methods for their detection and identification.
Internet: Look at the list of microbiology servers which I have compiled
at the URL: /sites.html#MBL.
This site has not been updated for about a year so if you find new informative
sites than please do let me know. I will add to them to the list.
Journals: Look up the following journals. The best would be look through
the journal volume index using Campylobacter as the key word. Some
journals that may be useful (but do not regard this as an exhaustive list)
are as follows:
Applied and Environmental Microbiology
FEMS Microbiology (Letters, Reviews)
Food Microbiology (access via the internet through IDEAL - check with the
library for access)
Journal of Clinical Microbiology
Books: Check up for books on Campylobacter. This could be an entire
book on this subject or may be chapters in books (e.g. The Prokaryotes
which comes in 4 volumes). Check the library catalogues for this information.